CASE STUDY AND RECENT PROJECTS

Location: Australia

• Project Type: Formulation and Manufacturing Services (one-stop solutions)

• ProbioWorld Group collaborated with industry partners to develop a one-stop solution—a scientifically formulated additive designed to enhance both dental and gut health in pets. Our expertise in product formulation, probiotic innovation, regulatory compliance, and product testing enabled us to create a potent and unique pet health formulation and product that meets industry standards.

• ✅ Develop an effective dual-action additive for dog dental and gut health
  ✅ Ensure scientific validation through in vitro analysis and product testing
  ✅ Achieve regulatory compliance for market readiness

• 🔬 Research & Formulation – Identified and developed bioactive ingredients supporting oral and gut health using traditional and advanced machine learning methods.
  🏭 Manufacturing – Scaled up production using GMP-compliant facilities for quality assurance.
  🧪 In Vitro Analysis & Testing – Validated efficacy through lab-based testing and microbial profiling
  ✅ Regulatory Compliance – Ensured adherence to pet health industry standards in Australia
  

• 🚀 A scientifically-backed additive formulated and designed to promote dental hygiene and digestive balance in dogs and other pets
  📈 Market-ready formulation that meets industry standards and pet owner expectations
  🔍 Proven efficacy through rigorous lab testing and validation

Partner with ProbioWorld Group to bring scientifically formulated pet health solutions to market.

📩 Contact us today to discuss your project!

  Location: New Zealand

• Project Type: Consulting Service

• With the Therapeutic Goods Administration (TGA) releasing a new probiotic policy on 15 January 2025, businesses in the probiotic industry needed clarity on compliance, formulation adjustments, and regulatory pathways. ProbioWorld Group was engaged to provide expert guidance and ensure a smooth transition for stakeholders navigating these regulatory changes.

• To deliver a comprehensive and actionable strategy, our team executed the following:
• ✔ Research & Data Mining – Analysed the TGA’s updated regulatory framework, comparing it with global probiotic standards.
  ✔ Consulting & Advisory Services – Provided expert insights on policy implications, compliance strategies, and formulation adjustments.
  ✔ Reporting & Documentation – Delivered a structured report addressing all industry concerns, outlining key action points for businesses to remain compliant.

Deliverables & Outcomes

• 📌 Consulting Session – A dedicated session where we addressed client-specific concerns and provided strategic recommendations.
  📌 Comprehensive Regulatory Report – A well-structured document detailing responses to questions on the policy and its implementation for probiotic businesses in New Zealand and Australia.

• ✅ Enabled seamless adaptation to the new policy with a clear compliance framework to support regulatory audit.
  ✅ Provided data-backed insights to inform business strategies and product formulation decisions.
  ✅ Strengthened client confidence in navigating regulatory changes effectively.

Navigating evolving probiotic regulations? ProbioWorld Group specialises in regulatory consulting, compliance strategies, and formulation support.

📩 Contact us today to ensure your probiotic products meet the latest standards with confidence!

 Location: Australia & UK

• Project Type: Formulation and manufacturing services (One-stop solutions)

CLIENT OBJECTIVE

• To develop an innovative, scientifically backed probiotic product that effectively reduces or eliminates alcohol hangovers in adults, providing a one-stop solution from concept to market.

• ProbioWorld Group collaborated with industry experts to deliver a comprehensive product development strategy, ensuring efficacy, compliance, and market readiness.

• ✅ Research & Formulation – Identified and developed formulation ingredients plus targeted probiotic strains to support alcohol metabolism and gut health.
  ✅ Manufacturing – Scaled up production using GMP-compliant facilities for quality assurance.
  ✅ In Vitro Analysis & Testing – Conducted controlled laboratory studies to validate the product’s effectiveness.
  ✅ Regulatory Compliance – Ensured adherence to regulatory guidelines for legal market entry.
  ✅ Labelling & Packaging – Worked with client on designing compliant and market-ready packaging aligned with regulatory and branding standards.

• 🔬 A scientifically validated probiotic formulation that aids in reducing or eliminating alcohol hangovers.
  🌍 Successfully developed product ready for Australian markets

Looking to develop a science-backed product line? Let’s create your next breakthrough product together!

📩 Contact Us Today to discuss your probiotic innovation needs.

 Location: New Zealand

• Project Type: Consulting Service

• ProbioWorld Group was engaged to provide a scientific interpretation of contract laboratory results to support risk assessment on batch releases of probiotic products. The goal was to justify the acceptance of results within a 0.5 log variation, ensuring that minor discrepancies did not lead to unnecessary product rejections.

To achieve this, our expert team conducted a thorough investigation, including:

• ✔ Analysis of Laboratory Procedures – Reviewing methodologies to identify potential sources of variation.
  ✔ Comprehensive Literature Search – Gathering scientific evidence to support the acceptance criteria.
  ✔ Data Analysis & Interpretation – Evaluating statistical trends and industry benchmarks.
  ✔ Detailed Report Compilation – Providing a structured justification for regulatory and business stakeholders.

• 📌 A comprehensive strategic report supporting the acceptance of 0.5 log variations in test results.
  📌 Evidence-based justification proving that deviations were not due to analyst error or product failure.
  📌 Actionable insights to refine quality assurance protocols and improve decision-making for batch releases.

• ✅ Ensured regulatory compliance and confidence in product integrity.
  ✅ Helped the client make informed risk-based decisions, reducing unnecessary product rejections.
  ✅ Strengthened quality control processes, improving industry best practices.

Our team at ProbioWorld Group specialises in providing data-driven insights for quality assurance, microbiological testing, and regulatory decision-making.

📩 Contact us today to discuss how we can support your business with expert scientific analysis and reporting.

 Location: United States

• Project Type: Formulation and Consultancy

• ProbioWorld Group served as the Subject Matter Expert (SME) in the development of a probiotic formulation designed to withstand high temperatures in tropical regions without the need for refrigeration. This innovation was crucial for expanding probiotic accessibility in markets where cold-chain storage is a challenge.

• ✔ Supported the design of a probiotic product with enhanced thermal stability for tropical climates
  ✔ Ensure viability and potency without refrigeration
  ✔ Provide strategic guidance to support the project's long-term success

• 🔬 Expert Consultation – Provided in-depth scientific and technical guidance on strain selection, formulation, and stability enhancement.
  🌍 Market-Specific Solutions – Addressed environmental and regulatory considerations for distribution in tropical regions.
  

• ✅ Successfully designed a thermally stable probiotic formulation
  

Partner with ProbioWorld Group for expert guidance in probiotic formulation and product development.

📩 Contact Us Today to discuss your next project!

Location: Australia

• Project Type: Consulting Service 

• A leading probiotic manufacturer faced consistently low viability and reduced counts for multistrain probiotic Products across multiple contract testing laboratories in Australia and the United States. This variability raised concerns regarding product quality, regulatory compliance, and market readiness.

• The Probioworld Group team conducted a comprehensive investigation to identify the root causes affecting product viability. Our expert-led troubleshooting process included:

• ✔ Product Ingredient Analysis – Assessing the impact of excipients and formulation components on probiotic survival.
  ✔ Method of Analysis Investigation – Evaluating inconsistencies in analytical techniques used across different laboratories.
  ✔ Manufacturing Process Analysis – Examining critical process parameters affecting probiotic stability.
  ✔ Analyst Competence Check – Ensuring laboratory personnel followed industry best practices for probiotic testing.

• 🔹 Method Optimisation – Adjusted testing protocols to account for non-probiotic ingredients impacting viability.
• 🔹 Engaged flow cytometry and plating methods to account for multistrain different growth conditions
• 🔹 Enhanced Accuracy & Consistency – Identified and standardised best practices to minimise result discrepancies.
• 🔹 Improved Product Stability – Provided strategic recommendations for formulation adjustments.

• Through our expertise in probiotic formulation and analytical troubleshooting, the client successfully achieved consistent, reliable viability results, ensuring regulatory compliance and enhanced product confidence in global markets.

📩 Facing probiotic viability challenges? 

Contact us today to optimise your testing methods and product stability!